|本期目录/Table of Contents|

Euplotid细胞核反常密码的建模研究(PDF)

《内蒙古大学学报(自然科学版)》[ISSN:1000-9035/CN:22-1262/O4]

期数:
2019年06期
页码:
637-642
栏目:
研究论文
出版日期:
2019-11-15

文章信息/Info

Title:
Model Building Research on Euplotid Deviant Codes
作者:
孙咏萍
内蒙古师范大学物理与电子信息学院,呼和浩特 010022
Author(s):
SUN Yong-ping
College of Physics and Electronic Information,Inner Mongolia Normal University,Hohhot 010022,China
关键词:
游仆虫 终止密码 反常密码 突变危险性极小 遗传密码
Keywords:
Euplotid stop codons deviant code mutational deterioration minimization genetic code
分类号:
-
DOI:
-
文献标识码:
A
摘要:
以NCBI数据库中游仆虫细胞核(Euplotid)反常密码为典型案例进行建模研究,证明游仆虫(Euplotid)反常密码在进化中遵循的数理逻辑与精髓——自然选择压力下的编码关系是一定约束前提下的总体突变危险性极小码; 模型可为量化编码关系,为遗传密码的扩张、进化、基因工程及蛋白质的改造提供数理依据.
Abstract:
Based on the model building research on Euplotid deviant codes provided by NCBI databases,a mathematical physics logic of the code relationship is deduced and proved.The deviant codes selected by nature are actually a minimal representation of Global Mutational Deterioration.The model can offer a quantifiable approach and mathematical physics basis towards codon expansion,genetic engineering and protein modification.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期:2019-03-13; 修回日期:2019-04-08
基金项目:内蒙古自然科学基金资助项目(2016MS0365); 国家社会科学基金资助项目(17XSS001)
作者简介:〖JP2〗孙咏萍(1979-),女,内蒙古兴安盟人,副教授,博士.主要从事生物物理学及科学史研究.E-mail:ypsun@imnu.edu.cn
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